Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 8/20 | 0.42 |
| ▸ | CES1 | P23141 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7757124 | 0.94 | CES2 (0.39) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7760148 | 0.89 | CES2 (0.42) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7760151 | 0.89 | HSD17B10 (0.40) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7761197 | 0.88 | CES2 (0.47) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7757123 | 0.81 | CES2 (0.39) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL27534637 | 0.81 | CES2 (0.48) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL27571528 | 0.80 | HSD17B10 (0.38) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL27372386 | 0.79 | CES2 (0.52) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL4830272 | 0.78 | CES2 (0.61) | CES2LPAR1LPAR3FAAHCES1 | |
| SCHEMBL7757145 | 0.78 | CES2 (0.40) | CES2LPAR1LPAR3FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |