Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1805633 | 0.91 | BRD4 (0.53) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL2861951 | 0.89 | BRD4 (0.51) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL176614 | 0.89 | BRD4 (0.51) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL30092569 | 0.89 | BRD4 (0.50) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL3824812 | 0.89 | BRD4 (0.50) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL7908182 | 0.89 | CYP3A4 (0.44) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL31697699 | 0.87 | BRD4 (0.49) | BRD4TP53CREBBPALDH1A1L3MBTL1 | |
| SCHEMBL1755154 | 0.87 | BRD4 (0.49) | BRD4TP53CREBBPCYP3A4TSHR | |
| SCHEMBL1755030 | 0.87 | BRD4 (0.49) | BRD4TP53CREBBPALDH1A1L3MBTL1 | |
| SCHEMBL7032447 | 0.87 | CYP3A4 (0.48) | BRD4TP53CREBBPCYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581617-A1 | COMPOSITIONS COMPRISING A FILM-FORMING POLYMER AND AN AROMATIC ACID OR SALT THEREOF, AND PREPARATION AND USES THEREOF | Synthomer (UK) Ltd. (GB) | 2019-12-18 | — | — | EP | disclosed |
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2014-03-06 | — | — | US | disclosed |
| EP-2677865-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | Icahn School of Medicine at Mount Sinai (US) | 2014-01-01 | — | — | EP | disclosed |
| EP-1697467-B1 | TRISAZO-DYESTUFFS | FUJIFILM IMAGING COLORANTS LTD (GB) | 2012-12-26 | — | — | EP | disclosed |
| WO-2012116170-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | ZHOU MING-MING (US) | 2012-08-30 | — | — | WO | disclosed |
| US-7638609-B2 | Trisazo-dyestuffs | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-12-29 | — | — | US | disclosed |
| US-7638609-B2 | Trisazo-dyestuffs | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2009-12-29 | — | — | US | disclosed |
| US-20070062409-A1 | Trisazo-dyestuffs | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2007-03-22 | — | — | US | disclosed |
| US-20070062409-A1 | Trisazo-dyestuffs | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2007-03-22 | — | — | US | disclosed |
| EP-0719841-B1 | Mixture of water soluble reactive azo dyes, process to manufacture it and its use | DYSTAR TEXTILFARBEN GMBH & CO (DE) | 2001-03-14 | — | — | EP | disclosed |
| EP-0126405-A1 | Pyrazolone azo dyestuffs | BASF Aktiengesellschaft (DE) | 1984-11-28 | — | — | EP | disclosed |
| EP-0115705-A2 | Monoazo compound having both monochlorotriazinyl and vinylsulfone type reactive groups | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-15 | — | — | EP | disclosed |
| US-4424153-A | ARYLAZO-AZO-METHINE | BASF AKTIENGESELLSCHAFT (DE) | 1984-01-03 | — | — | US | disclosed |
| EP-0047427-B1 | 1:2-CHROMIUM COMPLEX DYESTUFFS CONTAINING SULFONIC-ACID GROUPS | BASF Aktiengesellschaft (DE) | 1983-05-18 | — | — | EP | disclosed |
| US-4336322-A | DYE RELEASING REDOX COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1982-06-22 | — | — | US | disclosed |
| EP-0052985-A1 | Reactive monoazo scarlet dyes | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-06-02 | — | — | EP | disclosed |
| EP-0047427-A1 | 1:2-Chromium complex dyestuffs containing sulfonic-acid groups | BASF Aktiengesellschaft (DE) | 1982-03-17 | — | — | EP | disclosed |
| US-4255509-A | NAPHTHYL-AZO-PHENYL COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1981-03-10 | — | — | US | disclosed |
| US-4048154-A | POLYAMIDE FIBERS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |
| US-4035350-A | Process for the preparation of water-soluble azo dyestuffs by reacting an aromatic amine and a coupling component with alkali metal nitrite or alkyl nitrite in the absence of acid | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066410-A1 | INHIBITORS OF BROMODOMAINS AS MODULATORS OF GENE EXPRESSION | NFKBIA, NFKB2, IKBKG | BRD4 23/4885TP53 7/4885CREBBP 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.