SCHEMBL7757245

SCHEMBL7757245

CCCCC[SiH]1CCC(C2CCC(c3cc(F)c(-c4ccc(F)c(F)c4)c(F)c3)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCGR P47871 1/20 0.36
PDE5A O76074 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7757242 1.00 GCGR (0.36) GCGRPDE5A
SCHEMBL7757736 0.93 GCGR (0.31) GCGR
SCHEMBL8986505 0.93 GCGR (0.31) GCGR
SCHEMBL8396877 0.93 GCGR (0.39) GCGRPDE5A
SCHEMBL8396880 0.93 GCGR (0.39) GCGRPDE5A
SCHEMBL7757296 0.90 SPHK1 (0.34) GCGRPDE5A
SCHEMBL7756609 0.90 SPHK1 (0.34) GCGRPDE5A
SCHEMBL8021838 0.90 GCGR (0.32) GCGR
SCHEMBL8021835 0.90 GCGR (0.32) GCGR
SCHEMBL7756604 0.90 SPHK1 (0.34) GCGRPDE5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718387-B1 A liquid crystal composition and a liquid crystal display element which contains it SHINETSU CHEMICAL CO (JP) 2001-03-14 EP disclosed
US-5762826-A Liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1998-06-09 US disclosed
EP-0718387-A1 A liquid crystal composition and a liquid crystal display element which contains it SHIN-ETSU CHEMICAL CO., LTD. (JP) 1996-06-26 EP disclosed