Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL810099 | 0.78 | — | — | |
| SCHEMBL8895771 | 0.76 | CHRM1 (0.50) | CES2CES1ALDH1A1TP53 | |
| SCHEMBL3126476 | 0.75 | — | — | |
| SCHEMBL14160266 | 0.74 | — | — | |
| SCHEMBL3644715 | 0.74 | CES2 (0.46) | CES2CES1ALDH1A1TP53 | |
| SCHEMBL434439 | 0.74 | CES2 (0.46) | CES2CES1ALDH1A1TP53CA1 | |
| SCHEMBL5688270 | 0.74 | — | — | |
| SCHEMBL22115919 | 0.74 | CES2 (0.46) | CES2CES1ALDH1A1TP53CA1 | |
| SCHEMBL22115920 | 0.74 | CES2 (0.46) | CES2CES1ALDH1A1TP53CA1 | |
| SCHEMBL27353021 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882007-B1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-6031139-A | Preparation of α-fluoroketones | F2 CHEMICALS LIMITED (GB) | 2000-02-29 | — | — | US | disclosed |
| EP-0882007-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 Chemicals Limited (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997046508-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LIMITED (GB) | 1997-12-11 | — | — | WO | disclosed |
| US-4215044-A | FLUORINATION OF AN UNSATURATED SILANOL COMPOUND WITH A PERHALOGENATED HYPOFLUORITE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-07-29 | — | — | US | disclosed |