SCHEMBL7757623

SCHEMBL7757623

[N]=Nc1nsc2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.52
MAPT P10636 2/20 0.52
ALDH1A1 P00352 1/20 0.52
HSD17B10 Q99714 1/20 0.52
EPAS1 Q99814 8/20 0.44
MMP13 P45452 5/20 0.40
GPR3 P46089 1/20 0.37
MMP3 P08254 5/20 0.37
EPHX2 P34913 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5348534 0.74 KDM4E (0.47) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL11654916 0.73 MAPT (0.56) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL28563540 0.72 MAPT (0.60) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL30987223 0.72 MAPT (0.60) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL8684787 0.70 KDM4E (0.43) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL7609896 0.69 MAPT (0.53) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL11331077 0.69 EPAS1 (0.51) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL911402 0.68 MAPT (0.56) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL3810651 0.68 MAPT (0.56) KDM4EMAPTALDH1A1HSD17B10EPAS1
SCHEMBL12329 0.68 MAPT (0.56) KDM4EMAPTALDH1A1HSD17B10EPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109608901-A A kind of preparation method of benzisothiazole-azo dispersed blue dye 绍兴市上虞鼎诚化工有限公司 2019-04-12 CN claimed
EP-0591736-B1 Use of pyridine dyes for textiles, mixtures of dyes containing pyridine dyes, and triazolopyridine dyes with a thienyl radical BASF AG (DE) 2001-04-04 EP claimed
US-5376150-A Use of pyridine dyes in the textile sector, dye mixtures with pyridine dyes, and triazolopyridine dyes having a thienyl radical BASF AKTIENGESELLSCHAFT (DE) 1994-12-27 US claimed
EP-0390024-B1 Azodyes with a diazo component of the aminobenzoisothiazole series BASF AG (DE) 1994-06-08 EP claimed
US-5175265-A Useful for dyeing synthetic fibers, such as polyamides, polyesters and cellulose esters BASF AKTIENGESELLSCHAFT (DE) 1992-12-29 US claimed
US-4650860-A BLUE SHADES ON COTTON BASF AKTIENGESELLSCHAFT (DE) 1987-03-17 US claimed
EP-0084150-B1 BENZISOTHIAZOLE AZO DYESTUFFS BASF Aktiengesellschaft (DE) 1985-04-10 EP claimed
CN-109608901-A A kind of preparation method of benzisothiazole-azo dispersed blue dye 绍兴市上虞鼎诚化工有限公司 2019-04-12 CN disclosed
CN-109608901-A A kind of preparation method of benzisothiazole-azo dispersed blue dye 绍兴市上虞鼎诚化工有限公司 2019-04-12 CN disclosed
CN-109608901-A A kind of preparation method of benzisothiazole-azo dispersed blue dye 绍兴市上虞鼎诚化工有限公司 2019-04-12 CN disclosed
US-6124084-A AZO DYES; GOOD FASTNESS TO COLOR, HUMIDITY AND HEAT FUJI PHOTO FILM CO., LTD. (JP) 2000-09-26 US disclosed
EP-0569759-B1 Benzisothiazolazo dyes with a coupling component of the aniline series BASF AG (DE) 1997-08-13 EP disclosed
US-5376150-A Use of pyridine dyes in the textile sector, dye mixtures with pyridine dyes, and triazolopyridine dyes having a thienyl radical BASF AKTIENGESELLSCHAFT (DE) 1994-12-27 US disclosed
US-5175265-A Useful for dyeing synthetic fibers, such as polyamides, polyesters and cellulose esters BASF AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
US-5175265-A Useful for dyeing synthetic fibers, such as polyamides, polyesters and cellulose esters BASF AKTIENGESELLSCHAFT (DE) 1992-12-29 US disclosed
EP-0400451-A1 Benzisothiazolazo dyes with a coupling component of thiazole or pyridine series BASF Aktiengesellschaft (DE) 1990-12-05 EP disclosed
US-4650860-A BLUE SHADES ON COTTON BASF AKTIENGESELLSCHAFT (DE) 1987-03-17 US disclosed
EP-0030318-A2 Monoazo dyestuffs of the benzisothiazolazo aniline series and their use in dyeing synthetic fibres BASF Aktiengesellschaft (DE) 1981-06-17 EP disclosed