Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387534 | 0.85 | ALDH1A1 (0.56) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL11310945 | 0.83 | LCK (0.58) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL3617721 | 0.83 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL7802404 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL2366676 | 0.80 | KDM4E (0.51) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL1743592 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL31535290 | 0.80 | LCK (0.65) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL8901996 | 0.79 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL6743024 | 0.79 | LCK (0.58) | KDM4EALDH1A1HPGDLCKFYN | |
| SCHEMBL2337780 | 0.79 | HTT (0.51) | KDM4EALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001056982-A1 | VITAMIN D-DERIVATIVES AND THEIR USE IN TREATING OSTEOPOROSIS AND RELATED BONE DISORDERS | LEO PHARMA A/S (DK) | 2001-08-09 | — | — | WO | disclosed |