Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.48 |
| ▸ | KCNJ1 | P48048 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783167 | 0.89 | TSHR (0.49) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL88305 | 0.84 | TSHR (0.55) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7975582 | 0.83 | TSHR (0.50) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7083059 | 0.83 | TSHR (0.53) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7758234 | 0.83 | TSHR (0.53) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL5836815 | 0.81 | THRB (0.34) | TSHRALDH1A1 | |
| SCHEMBL4985770 | 0.80 | TSHR (0.58) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL7057603 | 0.80 | TSHR (0.58) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL3656180 | 0.80 | TSHR (0.62) | TSHRKCNH2KCNJ1IDO1LOXL2 | |
| SCHEMBL11025252 | 0.78 | TSHR (0.51) | TSHRKCNH2KCNJ1IDO1LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661291-B1 | Solid phase synthesis of oligoribonucleotide | AVENTIS PHARMA GMBH (DE) | 2001-03-07 | — | — | EP | disclosed |
| US-5866700-A | Solid-phase synthesis of oligoribonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-02-02 | — | — | US | disclosed |
| US-5652358-A | Solid-phase synthesis of oligoribonucleotides | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-07-29 | — | — | US | disclosed |
| EP-0661291-A1 | Solid phase synthesis of oligoribonucleotide | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |