SCHEMBL7757920

SCHEMBL7757920

C[C@@H](NC(=O)[C@@H](NC(=O)OCc1ccccc1)C(Cc1ccccc1)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.59
ECE1 P42892 1/20 0.59
CAPN1 P07384 1/20 0.56
ACE P12821 6/20 0.53
CTSL P07711 1/20 0.53
CTSS P25774 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10801569 0.92 MMP8 (0.54) MMEECE1CAPN1CTSLCTSS
SCHEMBL7759227 0.89 ECE1 (0.62) MMEECE1CTSLCTSS
SCHEMBL8762374 0.89 MME (0.48) MMEECE1CAPN1CTSLCTSS
SCHEMBL11792700 0.88 CYP3A4 (0.52) MMEECE1CTSLCTSS
SCHEMBL951587 0.87 MME (0.60) MMEECE1CAPN1CTSLCTSS
SCHEMBL9829372 0.87 MME (0.60) MMEECE1CAPN1CTSLCTSS
SCHEMBL19776145 0.87 MME (0.60) MMEECE1CAPN1CTSLCTSS
SCHEMBL11148538 0.86 MME (0.58) MMEECE1CTSLCTSS
SCHEMBL7757126 0.86 ECE1 (0.63) MMEECE1CTSLCTSS
SCHEMBL8649710 0.86 ECE1 (0.52) MMEECE1CTSLCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994002441-A1 A PROCESS FOR MAKING 1-CYCLOPENTYLALKYL AMINES USEFUL FOR THE SYNTHESIS OF SWEETENERS THE COCA-COLA COMPANY (US) 1994-02-03 WO claimed
US-5225591-A One-step reduction of an azanorbornene THE COCA-COLA COMPANY (US) 1993-07-06 US claimed
EP-0691346-B1 Novel aspartyldipeptide derivatives and sweetener AJINOMOTO KK (JP) 2001-03-14 EP disclosed
US-5723165-A ARTIFICIAL SWEETENERS AJINOMOTO CO., INC. (JP) 1998-03-03 US disclosed
EP-0779296-A2 D-alpha-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as intermediates for artificial sweeteners THE COCA-COLA COMPANY (US) 1997-06-18 EP disclosed
EP-0736037-A1 NOVEL INTERMEDIATES FOR THE SYNTHESIS OF L-ASPARTYL-D-$g(a)-AMINOALKANOYL-(S)-N-$g(a)-ALKYLBENZYL AMIDES USEFUL AS ARTIFICIAL SWEETENERS THE COCA-COLA COMPANY (US) 1996-10-09 EP disclosed
EP-0691346-A1 Novel aspartyldipeptide derivatives and sweetener Ajinomoto Co., Inc. (JP) 1996-01-10 EP disclosed
US-5286509-A L-aspartyl-D-α-aminoalkanoyl-(S)-N-alpha-alkylbenzyl amides useful as artificial sweeteners THE COCA-COLA COMPANY (US) 1994-02-15 US disclosed
WO-1994002441-A1 A PROCESS FOR MAKING 1-CYCLOPENTYLALKYL AMINES USEFUL FOR THE SYNTHESIS OF SWEETENERS THE COCA-COLA COMPANY (US) 1994-02-03 WO disclosed
US-5225591-A One-step reduction of an azanorbornene THE COCA-COLA COMPANY (US) 1993-07-06 US disclosed
US-4894464-A ARTIFICIAL SWEETENERS PFIZER INC. (US) 1990-01-16 US disclosed
US-4822635-A Sweetening with L-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1989-04-18 US disclosed
US-4804782-A ARTIFICIAL SWEETENER PFIZER, INC. (US) 1989-02-14 US disclosed
US-4788332-A ARTIFICAL SWEETENER GENERAL FOODS CORPORATION (US) 1988-11-29 US disclosed
US-4781927-A Sweetening with l-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-11-01 US disclosed
US-4766246-A L-aminodicarboxylic acid esters GENERAL FOODS CORPORATION (US) 1988-08-23 US disclosed
EP-0199257-A2 L-Aminodicarboxylic acid esters and an edible composition containing same as sweeteners GENERAL FOODS CORPORATION (US) 1986-10-29 EP disclosed
EP-0034876-B1 BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF PFIZER INC. (US) 1984-08-29 EP disclosed
US-4411925-A STABLE SWEETENERS PFIZER INC. (US) 1983-10-25 US disclosed
EP-0034876-A2 Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof PFIZER INC. (US) 1981-09-02 EP disclosed