SCHEMBL7757960

SCHEMBL7757960

C=Cc1cccc(OCCCCCCCCCCCCCCCCCC)c1

nearest known ligand 0.59

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.59
TLR4 O00206 1/20 0.54
TLR2 O60603 1/20 0.54
SMPD1 P17405 3/20 0.50
PLA2G4B P0C869 3/20 0.48
LTA4H P09960 1/20 0.47
GGPS1 O95749 2/20 0.47
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
CYSLTR2 Q9NS75 1/20 0.46
ALOX5 P09917 1/20 0.45
NR5A1 Q13285 1/20 0.45
GPBAR1 Q8TDU6 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8402393 1.00 TSHR (0.59) TSHRTLR4TLR2SMPD1PLA2G4B
SCHEMBL2623211 1.00 TSHR (0.59) TSHRTLR4TLR2SMPD1PLA2G4B
SCHEMBL10071520 1.00 TSHR (0.59) TSHRTLR4TLR2SMPD1PLA2G4B
SCHEMBL2623207 0.98 TSHR (0.57) TSHRTLR4TLR2SMPD1PLA2G4B
Dimethylamine SCHEMBL4361280 0.95 TSHR (0.55) TSHRTLR4TLR2SMPD1PLA2G4B
Dimethylamine SCHEMBL3445667 0.94 TSHR (0.53) TSHRTLR4TLR2SMPD1PLA2G4B
SCHEMBL412094 0.93 TLR4 (0.60) TSHRTLR4TLR2LTA4HTHRB
Diethylamine SCHEMBL3445792 0.93 TSHR (0.52) TSHRTLR4TLR2SMPD1PLA2G4B
Diethylamine SCHEMBL3444913 0.91 TSHR (0.50) TSHRTLR4TLR2SMPD1PLA2G4B
SCHEMBL3445340 0.90 TSHR (0.50) TSHRTLR4TLR2SMPD1PLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0699952-B1 A novel core-shell latex for use in photographic materials AGFA GEVAERT NV (BE) 2001-05-16 EP disclosed
EP-0643326-B1 New type of polymer latex and its use as plasticizer in a photographic material AGFA GEVAERT NV (BE) 1999-12-01 EP disclosed
EP-0703505-B1 Toner for two-component type developer MITA INDUSTRIAL CO LTD (JP) 1999-07-14 EP disclosed
US-5750301-A BINDER RESINS WITH ANIONIC GROUPS AND GRAFTED WAX WITH MAGNETIC POWDERS MITA INDUSTRIAL CO., LTD. (JP) 1998-05-12 US disclosed
EP-0520394-B1 Photographic element containing stress absorbing intermediate layer EASTMAN KODAK CO (US) 1997-10-01 EP disclosed
EP-0535535-B1 Photographic silver halide material with improved color saturation EASTMAN KODAK CO (US) 1997-07-30 EP disclosed
US-5561034-A HYDROPHILIC ADDITIONAL CORE-SHELL COPOLYMERS; DIMENSIONAL STABILITY, WEAR RESISTANCE, WATER ABSORPTION AGFA-GEVAERT, N.V. (BE) 1996-10-01 US disclosed
EP-0704768-A1 Toner for a two-component type developer MITA INDUSTRIAL CO., LTD. (JP) 1996-04-03 EP disclosed
EP-0703505-A1 Toner for two-component type developer MITA INDUSTRIAL CO., LTD. (JP) 1996-03-27 EP disclosed
EP-0699952-A1 A novel core-shell latex for use in photographic materials AGFA-GEVAERT N.V. (BE) 1996-03-06 EP disclosed
US-5478710-A Obtained by radical emulsion polymerization; glass transition temperature AGFA-GEVAERT, N.V. (BE) 1995-12-26 US disclosed
EP-0643326-A1 New type of polymer latex and its use as plasticizer in a photographic material AGFA-GEVAERT N.V. (BE) 1995-03-15 EP disclosed
US-5310639-A Photographic element containing stress absorbing intermediate layer EASTMAN KODAK COMPANY (US) 1994-05-10 US disclosed
US-5300417-A Blend of polymer and hydrophilic colloid EASTMAN KODAK COMPANY (US) 1994-04-05 US disclosed
US-5298376-A Photographic silver halide material with improved color saturation EASTMAN KODAK COMPANY (US) 1994-03-29 US disclosed
EP-0535535-A1 Photographic silver halide material with improved color saturation EASTMAN KODAK COMPANY (US) 1993-04-07 EP disclosed
EP-0520393-A1 Photographic element containing stress absorbing protective layer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-30 EP disclosed
EP-0520394-A2 Photographic element containing stress absorbing intermediate layer EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1992-12-30 EP disclosed
EP-0358187-A2 Tabular grain photographic elements exhibiting reduced pressure sensitivity (II) EASTMAN KODAK COMPANY (US) 1990-03-14 EP disclosed