Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.51 |
| ▸ | TLR2 | O60603 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.42 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL4361280 | 0.98 | TSHR (0.55) | TSHRTLR4TLR2SMPD1LTA4H | |
| Dimethylamine SCHEMBL3445676 | 0.95 | TLR4 (0.56) | TSHRTLR4TLR2SMPD1LTA4H | |
| SCHEMBL2623207 | 0.95 | TSHR (0.57) | TSHRTLR4TLR2SMPD1LTA4H | |
| SCHEMBL2623211 | 0.94 | TSHR (0.59) | TSHRTLR4TLR2SMPD1LTA4H | |
| SCHEMBL7757960 | 0.94 | TSHR (0.59) | TSHRTLR4TLR2SMPD1LTA4H | |
| SCHEMBL10071520 | 0.94 | TSHR (0.59) | TSHRTLR4TLR2SMPD1LTA4H | |
| SCHEMBL8402393 | 0.94 | TSHR (0.59) | TSHRTLR4TLR2SMPD1LTA4H | |
| Diethylamine SCHEMBL3444913 | 0.91 | TSHR (0.50) | TSHRTLR4TLR2SMPD1LTA4H | |
| Dimethylamine SCHEMBL4375978 | 0.91 | TLR4 (0.47) | TSHRTLR4TLR2KMT2ANR1H4 | |
| SCHEMBL412094 | 0.91 | TLR4 (0.60) | TSHRTLR4TLR2LTA4HKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7816475-B2 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION (JP) | 2010-10-19 | — | — | US | disclosed |
| US-20070213490-A1 | Aminoalkoxystyrene, process for preparation thereof, polymer thereof, process for producing the polymer and use thereof | TOSOH CORPORATION | 2007-09-13 | — | — | US | disclosed |