Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxamate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 2/20 | 0.90 |
| ▸ | LDHB | P07195 | 1/20 | 0.90 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxamate SCHEMBL11620 | 0.95 | — | — | |
| Oxamate SCHEMBL2109206 | 0.95 | LDHA (1.00) | LDHALDHBACHELMNATDP1 | |
| Oxamate SCHEMBL2558688 | 0.90 | — | — | |
| Oxamate SCHEMBL5710751 | 0.90 | LDHA (0.90) | LDHALDHBACHELMNATDP1 | |
| Oxamate SCHEMBL3888428 | 0.90 | — | — | |
| Oxamate SCHEMBL1258135 | 0.90 | — | — | |
| Oxamate SCHEMBL4394181 | 0.90 | — | — | |
| Oxamate SCHEMBL30377084 | 0.90 | LDHA (0.90) | LDHALDHBACHELMNATDP1 | |
| Oxamate SCHEMBL2541414 | 0.90 | — | — | |
| Oxamate SCHEMBL29210043 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850927-B1 | Novel oxalic acid peroxide compositions and their uses | ATOFINA CHEM INC (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5866712-A | POLYMERIZATION AND CURING CATALYSTS | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0850927-A1 | Novel oxalic acid peroxide compositions and uses | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1998-07-01 | — | — | EP | disclosed |