SCHEMBL7757995

SCHEMBL7757995

CCC(C)(C)C(=O)C(=O)N1CCCC[C@H]1C(=O)SCCC(c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 16/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677088 1.00 FKBP1A (1.00) FKBP1A
SCHEMBL7761797 0.98 FKBP1A (1.00) FKBP1A
SCHEMBL4678702 0.85 FKBP1A (0.94) FKBP1A
SCHEMBL18254879 0.84 FKBP1A (1.00) FKBP1A
SCHEMBL4680563 0.84 FKBP1A (0.89) FKBP1A
SCHEMBL4677178 0.84 FKBP1A (0.75) FKBP1A
SCHEMBL5834087 0.82 FKBP1A (1.00) FKBP1A
SCHEMBL4680521 0.81 FKBP1A (0.73) FKBP1A
SCHEMBL4677091 0.80 FKBP1A (0.82) FKBP1A
SCHEMBL4679849 0.80 FKBP1A (0.72) FKBP1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410995-B1 N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders GPI NIL HOLDINGS INC. (US) 2008-08-12 US disclosed
US-7410995-B1 N-linked sulfonamide of heterocyclic thioesters for vision and memory disorders GPI NIL HOLDINGS INC. (US) 2008-08-12 US disclosed
US-7338976-B1 Heterocyclic esters or amides for vision and memory disorders GPI NIL HOLDINGS, INC. (US) 2008-03-04 US disclosed
US-7338976-B1 Heterocyclic esters or amides for vision and memory disorders GPI NIL HOLDINGS, INC. (US) 2008-03-04 US disclosed
US-7265150-B1 Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders GPI NIL HOLDINGS INC. (US) 2007-09-04 US disclosed
US-7265150-B1 Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds for vision and memory disorders GPI NIL HOLDINGS INC. (US) 2007-09-04 US disclosed
US-6506788-B1 Drugs and methods of using an N-linked urea or carbamate of a heterocyclic thioester for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance. GPI NIL HOLDINGS, INC. 2003-01-14 US disclosed
US-6506788-B1 Drugs and methods of using an N-linked urea or carbamate of a heterocyclic thioester for treating a vision disorder, improving vision, treating memory impairment, or enhancing memory performance. GPI NIL HOLDINGS, INC. 2003-01-14 US disclosed