SCHEMBL7758024

SCHEMBL7758024

C=CCOC(=O)OCC=C.C=CCOC(=O)OCCOCCOC(=O)OCC=C

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.52
ALDH1A1 P00352 5/20 0.52
TP53 P04637 2/20 0.52
HIF1A Q16665 2/20 0.52
HSD17B10 Q99714 2/20 0.52
TDP1 Q9NUW8 1/20 0.42
CYP3A4 P08684 2/20 0.39
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
THRB P10828 2/20 0.35
NPSR1 Q6W5P4 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SNCA P37840 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
APP P05067 1/20 0.31
SERPINE1 P05121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10870570 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL50692 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL188647 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL9714112 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL1093745 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL10886350 1.00 TSHR (0.52) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL8780696 0.96 TSHR (0.48) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL4386153 0.94 TSHR (0.47) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL176184 0.93 CYP3A4 (0.43) TSHRALDH1A1TP53HIF1AHSD17B10
SCHEMBL23222432 0.92 TSHR (0.45) TSHRALDH1A1TP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0850928-B1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ATOFINA CHEM INC (US) 2001-10-31 EP disclosed
EP-0850929-B1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ATOFINA CHEM INC (US) 2001-06-27 EP disclosed
EP-0850927-B1 Novel oxalic acid peroxide compositions and their uses ATOFINA CHEM INC (US) 2001-03-14 EP disclosed
US-5981787-A INITIATORS FOR POLYMERIZING ETHYLENICALLY UNSATURATED MONOMERS AND FOR CURING OF UNSATURATED POLYESTER RESINS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-11-09 US disclosed
US-5866712-A POLYMERIZATION AND CURING CATALYSTS ELF ATOCHEM NORTH AMERICA, INC. (US) 1999-02-02 US disclosed
US-5837782-A POLYMERIZATION CATALYST ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-11-17 US disclosed
EP-0850928-A1 Novel peroxyoxalates derived from hydroxy-hydroperoxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0850929-A1 Novel bis(mono- and diperoxy-oxalates) derived from dihydroperoxides and alkyl and alkylperoxy halooxalates ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0850927-A1 Novel oxalic acid peroxide compositions and uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1998-07-01 EP disclosed
EP-0667339-B1 Novel unsaturated peroxides, polymeric peroxides derived therefrom and their uses ATOCHEM NORTH AMERICA ELF (US) 1998-05-06 EP disclosed
US-5399630-A Process for curing polymers using amino or hydrazino peroxides ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-03-21 US disclosed
EP-0355733-B1 Amino or hydrazino peroxides, derivatives and their uses ATOCHEM NORTH AMERICA (US) 1995-02-08 EP disclosed
US-5387654-A Hydroxy-peroxides and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-02-07 US disclosed
US-5360867-A Reactive with maleic acid or maleic anhydride polymer ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-11-01 US disclosed
EP-0381135-B1 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA (US) 1994-06-01 EP disclosed
US-5304649-A Curing agent for unsaturated polyesters ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-19 US disclosed
US-5272219-A Process for preparing amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1993-12-21 US disclosed
US-4956416-A CURING UNSATURATED POLYESTERS; ADDITION POLYMERIZATION CATALYSTS; COAVALENTLY BOUND PERFORMANCE ADDITIVE FUNCTIONS; GRAFT AND BLOCK POLYMERS; SELF-CURING ATOCHEM NORTH AMERICA, INC. (US) 1990-09-11 US disclosed
EP-0381135-A2 Novel hydroxy-peroxides and their uses ATOCHEM NORTH AMERICA, INC. (US) 1990-08-08 EP disclosed
EP-0355733-A1 Amino or hydrazino peroxides, derivatives and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1990-02-28 EP disclosed