Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886350 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL1093745 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9714112 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL50692 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10870570 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL10902737 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL5860449 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7265581 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL7758024 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL188647 | 0.96 | TSHR (0.52) | TSHRALDH1A1TP53HIF1AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421512-A1 | Sensitisation and stabilisation of organometallic compounds acting as photocatalysts and photosensitisers in photochemical radical polymerisation process | CHIMIA PRODOTTI E PROCESSI SRL (IT) | 1991-04-10 | — | — | EP | claimed |
| EP-3740815-A1 | SPECTACLE LENS COMPRISING AT LEAST ONE NANOSTRUCTURED AND/OR MICRO-STRUCTURED LAYER | Carl Zeiss Vision International GmbH (DE) | 2020-11-25 | — | — | EP | disclosed |
| EP-0810251-A2 | Storage-stable one-component air activated formulations of polythiol and polyene employing iron compound | LOCTITE (IRELAND) LIMITED (IE) | 1997-12-03 | — | — | EP | disclosed |