SCHEMBL7758037

SCHEMBL7758037

CCCCCCCCCCC(C)CCC(O)=S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.55
FFAR1 O14842 2/20 0.41
FFAR4 Q5NUL3 1/20 0.41
MAPT P10636 2/20 0.41
GPR84 Q9NQS5 8/20 0.41
SPHK1 Q9NYA1 1/20 0.41
PRKD3 O94806 1/20 0.40
PRKCG P05129 1/20 0.40
PRKCB P05771 1/20 0.40
PRKCA P17252 1/20 0.40
PRKCH P24723 1/20 0.40
PRKCI P41743 1/20 0.40
PRKCE Q02156 1/20 0.40
PRKCQ Q04759 1/20 0.40
PRKCZ Q05513 1/20 0.40
PRKCD Q05655 1/20 0.40
PRKD1 Q15139 1/20 0.40
LMNA P02545 1/20 0.40
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18920279 1.00 ACE2 (0.55) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL8757696 0.91 ACE2 (0.47) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL17024432 0.82 TSHR (0.46) ACE2MAPTTSHR
SCHEMBL19068655 0.82 ACE2 (0.48) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL3716580 0.81 ACE2 (0.42) ACE2FFAR1FFAR4MAPTPRKD3
SCHEMBL11303854 0.81 ACE2 (0.52) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL9514194 0.81 ACE2 (0.52) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL25275005 0.79 ACE2 (0.66) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL2222385 0.79 ACE2 (0.66) ACE2FFAR1FFAR4MAPTGPR84
SCHEMBL16213113 0.79 ACE2 (0.66) ACE2FFAR1FFAR4MAPTGPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0764636-B1 Thiopropionate synergists GOODYEAR TIRE & RUBBER (US) 2001-03-07 EP disclosed
US-5672730-A OXIDATION RESIST STABILIZER FOR POLYMERIC BLENDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1997-09-30 US disclosed