Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759523 | 0.83 | CHRM2 (0.33) | GRM2CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7752933 | 0.81 | — | — | |
| SCHEMBL7765247 | 0.77 | KCNH2 (0.33) | — | |
| SCHEMBL7765244 | 0.77 | KCNH2 (0.33) | — | |
| SCHEMBL7758795 | 0.75 | TSHR (0.33) | CHRM2CHRM4CHRM5CHRM1DRD2 | |
| SCHEMBL7758047 | 0.74 | — | — | |
| SCHEMBL7760259 | 0.74 | KCNH2 (0.34) | — | |
| SCHEMBL7759928 | 0.73 | KCNH2 (0.32) | — | |
| SCHEMBL7755593 | 0.73 | KCNH2 (0.32) | GRM2 | |
| SCHEMBL3373521 | 0.73 | CYP1A2 (0.41) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |