Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758069 | 0.90 | — | — | |
| SCHEMBL7758031 | 0.86 | KDM4E (0.32) | LMNA | |
| SCHEMBL7758795 | 0.86 | TSHR (0.33) | KCNH2LMNA | |
| SCHEMBL9272010 | 0.83 | LMNA (0.33) | KCNH2LMNATDP1MEN1KMT2A | |
| SCHEMBL7760259 | 0.82 | KCNH2 (0.34) | KCNH2 | |
| SCHEMBL7763766 | 0.81 | KCNH2 (0.36) | KCNH2MEN1KMT2A | |
| SCHEMBL7765244 | 0.80 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL7765247 | 0.80 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL7759562 | 0.79 | MAPT (0.42) | LMNAPPARG | |
| SCHEMBL7759523 | 0.79 | CHRM2 (0.33) | KCNH2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |