SCHEMBL154177

SCHEMBL154177

Cc1cn([C@H]2CC[C@@H](COP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.65
POLA1 P09884 1/20 0.65
POLD1 P28340 1/20 0.65
TK1 P04183 7/20 0.57
BCHE P06276 1/20 0.49
ALB P02768 1/20 0.48
PKM P14618 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265387 0.98 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL3031874 0.98 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL30586988 0.98 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL77582 0.98 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL18855348 0.98 POLB (0.68) POLBPOLA1POLD1TK1BCHE
SCHEMBL28961478 0.96 POLB (0.61) POLBPOLA1POLD1TK1ALB
Triphosphate SCHEMBL27892350 0.95 POLB (0.61) POLBPOLA1POLD1TK1BCHE
SCHEMBL23440065 0.91 TK1 (0.67) POLBPOLA1POLD1TK1
SCHEMBL28774920 0.91 TK1 (0.67) POLBPOLA1POLD1TK1
SCHEMBL8883 0.91 TK1 (0.67) POLBPOLA1POLD1TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1356 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025072741-A1 PRESERVATIVES FOR MOLECULAR SAMPLE ANALYSIS WITH SAMPLE COLLECTION DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2025-04-03 WO claimed
US-12145951-B2 Inorganic-organic hybrid compounds including organic platinum-containing anions, for use in medicine KARLSRUHER INSTITUT FUR TECHNOLOGIE (DE) 2024-11-19 US claimed
CN-117265046-A Application of rhamnosyl transferase in rhamnosylation modification of natural product 山东大学 2023-12-22 CN claimed
CN-114903028-B Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2023-10-17 CN claimed
US-20230174991-A1 KDO-FREE PRODUCTION HOSTS FOR OLIGOSACCHARIDE SYNTHESIS INBIOSE N.V. (BE) 2023-06-08 US claimed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
US-20210292353-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2021-09-23 US claimed
EP-3829565-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2021-06-09 EP claimed
WO-2020025488-A1 INORGANIC-ORGANIC HYBRID COMPOUNDS INCLUDING ORGANIC PLATINUM-CONTAINING ANIONS, FOR USE IN MEDICINE Karlsruher Institut für Technologie (DE) 2020-02-06 WO claimed
CN-106660944-A Hybrid inorganic-organic compounds 卡尔斯鲁尔工学院 2017-05-10 CN claimed
US-20170112948-A1 Inorganic-organic hybrid compound Karlsruher Institut für Technologie (DE) 2017-04-27 US claimed
WO-2016168735-A1 NUCLEOSIDE SUPPLEMENTATION TO PROMOTE CELLULAR FUNCTION, GENETIC STABILITY AND AUGMENT TRANSGENIC EXPRESSION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-10-20 WO claimed
EP-3058061-A1 NUCLEOSIDE SUPPLEMENTATION TO PROMOTE CELLULAR FUNCTION, GENETIC STABILITY AND REGENERATIVE APPLICATIONS The Regents of the University of California (US) 2016-08-24 EP claimed
WO-2015057997-A1 NUCLEOSIDE SUPPLEMENTATION TO PROMOTE CELLULAR FUNCTION, GENETIC STABILITY AND REGENERATIVE APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2015-04-23 WO claimed
US-8956833-B2 Methods for control of flux in metabolic pathways through enzyme relocation GREENLIGHT BIOSCIENCES, INC. (US) 2015-02-17 US claimed
CN-101705269-A Method for synthesizing deoxythymidine triphosphate through biotechnology JIANGSU HUARONG BIOLOG TECHNOL 2010-05-12 CN claimed
US-6379898-B2 BY DEPOLYMERIZING DNA AT A TERMINAL NUCLEOTIDE ENZYMATIC CLEAVAGE WITH A PYROPHOSPHATE MOLECULE TO FORM A FREE DEOXYRIBONUCLEOSIDE TRIPHOSPHATE, AND REACTING WITH ADENOSINE 5'-DIPHOSPHATE TO FORM ATP WITH NUCLEOSIDE DIPHOSPHATE KINASE SHULTZ JOHN W (US) 2002-04-30 US claimed
EP-0579806-B1 MEDICAMENT FOR THE TREATMENT AND/OR PROPHYLAXIS OF FOLATE METABOLISM DISORDERS KRAGLER PETER (DE) 1999-07-07 EP claimed
EP-4749287-A2 METHOD Oxford University Innovation Limited (GB) 2026-05-27 EP disclosed
WO-1991006671-A1 MEANS FOR DETECTING HIGHLY PROLIFERATIVE CELLS INSTITUT PASTEUR (FR) 1991-05-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170112948-A1 Inorganic-organic hybrid compound SLCO4C1, SLCO2A1, SLCO1A2 POLB 3337/4885POLA1 2702/4885POLD1 2187/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.