Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.57 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.57 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337353 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL4227873 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8525522 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL27245024 | 1.00 | GPR84 (0.59) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL8653572 | 0.98 | GPR84 (0.56) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL7125730 | 0.95 | GPR84 (0.54) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL337767 | 0.95 | GPR84 (0.64) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL337012 | 0.95 | GPR84 (0.64) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL5547897 | 0.95 | GPR84 (0.64) | GPR84FFAR1MAPTLCKPPARD | |
| SCHEMBL9066915 | 0.95 | GPR84 (0.64) | GPR84FFAR1MAPTLCKPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11993600-B2 | Saturated spirocyclics as antiviral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2024-05-28 | — | — | US | disclosed |
| WO-2023107419-A1 | SATURATED SPIROCYCLICS AS ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |
| US-20230174531-A1 | SATURATED SPIROCYCLICS AS ANTIVIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2023-06-08 | — | — | US | disclosed |
| JP-2001151728-A | METHOD FOR PRODUCING ALICYCLIC DICARBOXYLIC ACID DERIVATIVE AND ALICYCLIC DICARBOXYLIC ACID DRIVATIVE | NISSAN CHEM IND LTD | 2001-06-05 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11993600-B2 | Saturated spirocyclics as antiviral agents | ACE, ACE2, PKD1 | GPR84 1360/4885FFAR1 329/4885MAPT 4475/4885 |
| US-20230174531-A1 | SATURATED SPIROCYCLICS AS ANTIVIRAL AGENTS | ACE, ACE2, PKD1 | GPR84 1360/4885FFAR1 329/4885MAPT 4475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.