SCHEMBL7758400

SCHEMBL7758400

CCCCCCCCCCCCCCCCCCCCCC[C@@H](OC(C)=O)C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.52
FFAR1 O14842 2/20 0.52
MAPT P10636 1/20 0.50
LCK P06239 1/20 0.50
PPARD Q03181 1/20 0.50
ZDHHC20 Q5W0Z9 1/20 0.50
ZDHHC2 Q9UIJ5 1/20 0.50
ACE2 Q9BYF1 1/20 0.47
CA2 P00918 1/20 0.44
FAAH O00519 2/20 0.44
GRIK1 P39086 1/20 0.43
GRIK2 Q13002 1/20 0.43
FFAR4 Q5NUL3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447024 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL4115973 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL2792012 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8864030 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8864069 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7758405 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL8192721 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7758415 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL7759354 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD
SCHEMBL28488945 1.00 GPR84 (0.52) GPR84FFAR1MAPTLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0650732-B1 NOVEL MEDICINAL COMPOSITION KIRIN BREWERY (JP) 2001-04-04 EP disclosed
US-6071884-A ADMINISTERING TO THE PATIENT ATLEAST ONE ALPHA-GALACTOSYLCERAMIDE TO TREAT THROMBOCYTOPENIA KIRIN BEER KABUSHIKI KAISHA (JP) 2000-06-06 US disclosed
US-6017892-A Method for accelerating marrow cell proliferation KIRAN BEER KABUSHIKI KAISHA (JP) 2000-01-25 US disclosed
US-5936076-A ANTITUMOR/ANTICARCINOGENIC AGENTS; IMMUNOSTIMULATORS; THERAPY AGAINST INFECTIONS, AQUIRED IMMUNE DEFICIENCY SYNDROME KIRIN BEER KABUSHIKI KAISHA (JP) 1999-08-10 US disclosed
EP-0609437-B1 NOVEL SPHINGOGLYCOLIPID AND USE THEREOF KIRIN BREWERY (JP) 1999-07-07 EP disclosed
US-5767092-A Treatment of radiation-damaged bone marrow using galactosyl ceramides KIRIN BEER KABUSHIKI KAISHA (JP) 1998-06-16 US disclosed
US-5631356-A Selective N-acylation of amino alcohols GIST-BROCADES, N.V. (NL) 1997-05-20 US disclosed
EP-0633875-B1 SELECTIVE N-ACYLATION OF AMINO ALCOHOLS GIST BROCADES NV (NL) 1997-01-02 EP disclosed
EP-0650732-A1 NOVEL MEDICINAL COMPOSITION KIRIN BEER KABUSHIKI KAISHA (JP) 1995-05-03 EP disclosed
EP-0609437-A1 NOVEL SPHINGOGLYCOLIPID AND USE THEREOF KIRIN BEER KABUSHIKI KAISHA (JP) 1994-08-10 EP disclosed