SCHEMBL7758449

SCHEMBL7758449

NC(=O)Nc1ccc(Cl)cc1F

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
NPC1 O15118 4/20 0.59
RAB9A P51151 3/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
HPGD P15428 1/20 0.59
KIF11 P52732 3/20 0.57
MEN1 O00255 3/20 0.56
CA12 O43570 1/20 0.55
CA1 P00915 1/20 0.55
CA2 P00918 1/20 0.55
CA9 Q16790 1/20 0.55
MAPT P10636 3/20 0.51
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
TAS1R2 Q8TE23 1/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.50
TDP1 Q9NUW8 1/20 0.49
NPSR1 Q6W5P4 2/20 0.48
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27775431 0.87 GRIK1 (0.53) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL19707984 0.85 KMT2A (0.66) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL11580520 0.84 KMT2A (0.52) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL3883922 0.83 KMT2A (0.63) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL9835394 0.83 KMT2A (0.63) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL19987513 0.81 KMT2A (0.61) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL349268 0.81 KMT2A (0.61) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL29683063 0.81 KDM4E (0.62) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL10310298 0.81 KMT2A (0.53) KMT2ANPC1RAB9ASMN1; SMN2HPGD
SCHEMBL3873599 0.81 KDM4E (0.62) KMT2ANPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN claimed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO claimed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US claimed
CN-103221388-A Novel sulfonamide compounds for inhibition of metastatic tumor growth METASIGNAL THERAPEUTICS INC 2013-07-24 CN claimed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN claimed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO claimed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US claimed
CN-111988996-B Improving yield of nut bearing plants UPL有限责任公司 2023-07-14 CN disclosed
US-11641859-B2 Enhanced yield in nut bearing plants UPL CORPORATION LTD. (MU) 2023-05-09 US disclosed
CN-111988996-A Increasing yield of nut bearing plants UPL有限责任公司 2020-11-24 CN disclosed
WO-2020023356-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE BRISTOL-MYERS SQUIBB COMPANY (US) 2020-01-30 WO disclosed
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 US disclosed
WO-2019161274-A1 ENHANCED YIELD IN NUT BEARING PLANTS UPL CORPORATION LTD. (MU) 2019-08-22 WO disclosed
CN-103221388-B For the novel sulfonamide compounds suppressing metastatic tumo(u)r to grow 维理生物技术公司 2016-09-28 CN disclosed
CN-103221388-A Novel sulfonamide compounds for inhibition of metastatic tumor growth METASIGNAL THERAPEUTICS INC 2013-07-24 CN disclosed
CN-101679432-A Heteroaryl compounds, compositions thereof, and their use as protein kinase inhibitors SIGNAL PHARM LLC 2010-03-24 CN disclosed
CN-1406110-A Enhancement of seed/fruit/nut yield from flowering plants UNIROYAL CHEM CO INC (US) 2003-03-26 CN disclosed
WO-2001064036-A1 ENHANCEMENT OF SEED/FRUIT/NUT YIELDS FROM FLOWERING PLANTS UNIROYAL CHEMICAL COMPANY, INC. (US) 2001-09-07 WO disclosed
US-6242385-B1 SEEDS OF LEGUME PLANTS, APPLYING TO FOLAGE DURING REPRODUCTION PHENYLUREA DERIVATIVES UNIROYAL CHEMICAL COMPANY, INC. 2001-06-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190254281-A1 ENHANCED YIELD IN NUT BEARING PLANTS NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885NPC1 1857/4885RAB9A 1813/4885
US-11641859-B2 Enhanced yield in nut bearing plants NUTF2, MYCBP, MYCBP2 KMT2A 2393/4885NPC1 1857/4885RAB9A 1813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.