Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7401967 | 0.84 | CHRM1 (1.00) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL5065834 | 0.81 | KMT2A (0.65) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL8685563 | 0.80 | KMT2A (0.68) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL6901583 | 0.80 | KMT2A (0.63) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7758700 | 0.77 | CHRM1 (0.62) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL9492300 | 0.74 | KMT2A (0.69) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7755543 | 0.74 | KMT2A (0.69) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8775322 | 0.73 | CHRM1 (0.59) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8775260 | 0.73 | CHRM1 (0.73) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8685481 | 0.73 | KMT2A (0.58) | CHRM1KMT2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0674635-B1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | SYNGENTA LTD (GB) | 2001-03-28 | — | — | EP | disclosed |
| EP-0674635-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994014803-A1 | QUINUCLIDINE DERIVATIVES AS SQUALENE SYNTHASE INHIBITORS | ZENECA LIMITED (GB) | 1994-07-07 | — | — | WO | disclosed |