Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.55 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.55 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758627 | 0.84 | CHRM1 (0.72) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL9430968 | 0.73 | CHRM1 (0.68) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL9492300 | 0.73 | KMT2A (0.69) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7755543 | 0.73 | KMT2A (0.69) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8775364 | 0.72 | KMT2A (0.61) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL9458699 | 0.71 | CHRM1 (0.69) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL8777872 | 0.71 | KMT2A (0.65) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7398071 | 0.71 | KMT2A (0.56) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL5065834 | 0.71 | KMT2A (0.65) | CHRM1KMT2ACHRM2CHRM4CHRM5 | |
| SCHEMBL7396790 | 0.71 | CHRM1 (1.00) | CHRM1KMT2ACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599937-A | Heteroaromatic quinuclidinenes, their use and preparation | PHARMACIA AB (SE) | 1997-02-04 | — | — | US | disclosed |
| EP-0640082-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | Pharmacia & Upjohn Aktiebolag (SE) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023395-A1 | HETEROAROMATIC QUINUCLIDINENES, THEIR USE AND PREPARATION | KABI PHARMACIA AB (SE) | 1993-11-25 | — | — | WO | disclosed |