Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.54 |
| ▸ | REN | P00797 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.44 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30434892 | 0.97 | ACE (0.52) | ACERENOPRK1OPRM1 | |
| SCHEMBL30040838 | 0.93 | ACE (0.49) | ACERENOPRK1OPRM1 | |
| SCHEMBL30361726 | 0.92 | ACE (0.57) | ACEOPRK1DPP4FAPDPP8 | |
| SCHEMBL29501732 | 0.91 | ACE (0.52) | ACERENOPRM1DPP4FAP | |
| SCHEMBL23625401 | 0.91 | ACE (0.50) | ACERENOPRK1OPRM1 | |
| SCHEMBL4388468 | 0.91 | ACE (0.50) | ACERENOPRK1OPRM1 | |
| SCHEMBL7760126 | 0.90 | ACE (0.53) | ACERENOPRK1 | |
| SCHEMBL29995105 | 0.90 | ACE (0.55) | ACEOPRK1DPP4FAPDPP8 | |
| SCHEMBL34464908 | 0.90 | ACE (0.55) | ACEOPRK1DPP4FAPDPP8 | |
| SCHEMBL7757708 | 0.89 | OPRK1 (0.55) | ACEOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068114-A1 | NOVEL PEPTIDES WITH ANTI-HYPERTENSIVE ACTIVITY | MONSANTO COMPANY (US) | 2001-09-20 | — | — | WO | disclosed |