Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.35 |
| ▸ | RARB | P10826 | 3/20 | 0.34 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.32 |
| ▸ | MERTK | Q12866 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7758913 | 1.00 | PDE5A (0.36) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7771520 | 0.94 | SPHK1 (0.41) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7771522 | 0.94 | SPHK1 (0.41) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7757296 | 0.93 | SPHK1 (0.34) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7756609 | 0.93 | SPHK1 (0.34) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7756604 | 0.93 | SPHK1 (0.34) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7757564 | 0.91 | CYP11B2 (0.34) | PDE5AP2RY14CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7757568 | 0.91 | CYP11B2 (0.34) | PDE5AP2RY14CYP17A1CYP11B1CYP11B2 | |
| SCHEMBL7758004 | 0.91 | CYP2C9 (0.35) | PDE5AGCGRSPHK1RARBRARA | |
| SCHEMBL7758012 | 0.91 | CYP2C9 (0.35) | PDE5AGCGRSPHK1RARBRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696591-B1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHINETSU CHEMICAL CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| EP-0673942-B1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | SHINETSU CHEMICAL CO (JP) | 2000-11-08 | — | — | EP | disclosed |
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |
| US-5659059-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-08-19 | — | — | US | disclosed |
| US-5641431-A | Silacyclohexanone compound and a method of preparing a silacyclohexane-type liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1997-06-24 | — | — | US | disclosed |
| US-5514824-A | Process for preparing silacyclohexane-base liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-07 | — | — | US | disclosed |
| EP-0696591-A1 | Process for preparing silacyclohexane-based liquid crystal compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0673942-A1 | Silacyclohexanone compounds as intermediates for the preparation of silacyclohexane-type liquid cristal compounds | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-09-27 | — | — | EP | disclosed |
| EP-0650969-A1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-05-03 | — | — | EP | disclosed |