Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 7/20 | 0.67 |
| ▸ | THRA | P10827 | 6/20 | 0.67 |
| ▸ | THRB | P10828 | 6/20 | 0.67 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | STS | P08842 | 4/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.53 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27455127 | 1.00 | HSD17B3 (0.67) | HSD17B3THRATHRBS1PR5HTR7 | |
| SCHEMBL31366289 | 1.00 | HSD17B3 (0.67) | HSD17B3THRATHRBS1PR5HTR7 | |
| SCHEMBL15743522 | 1.00 | HSD17B3 (0.67) | HSD17B3THRATHRBS1PR5HTR7 | |
| SCHEMBL13085794 | 0.87 | HSD17B3 (0.85) | HSD17B3THRATHRBHTR7STS | |
| SCHEMBL13085847 | 0.87 | HSD17B3 (0.85) | HSD17B3THRATHRBHTR7STS | |
| SCHEMBL11490234 | 0.87 | THRA (0.77) | HSD17B3THRATHRBS1PR5 | |
| SCHEMBL7934415 | 0.87 | THRA (0.77) | HSD17B3THRATHRBS1PR5 | |
| SCHEMBL15199330 | 0.86 | HSD17B3 (0.71) | HSD17B3THRATHRBS1PR5HTR7 | |
| SCHEMBL12303994 | 0.86 | HSD17B3 (0.71) | HSD17B3THRATHRBS1PR5HTR7 | |
| SCHEMBL507985 | 0.85 | HSD17B3 (0.62) | HSD17B3THRATHRBHTR7STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001076626-A2 | LIPOPHILIC AROMATIC ALDEHYDE AND KETONE DERIVATIVES AND THE USE THEREOF AS IMMUNOSTIMULANTS AND ADJUVANTS | GALENICA PHARMACEUTICALS, INC. (US) | 2001-10-18 | — | — | WO | disclosed |