Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8734150 | 0.86 | PDE7A (0.51) | PDE7ASMN1; SMN2PDE7BMAPTMEN1 | |
| SCHEMBL10923003 | 0.85 | PDE7A (0.65) | PDE7ASMN1; SMN2PDE7BMAPTMEN1 | |
| SCHEMBL224666 | 0.84 | PDE7A (0.60) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL8989706 | 0.81 | PDE7A (0.51) | PDE7ASMN1; SMN2PDE7BMAPTMEN1 | |
| SCHEMBL11209984 | 0.76 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11027382 | 0.76 | PDE7A (0.56) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11319431 | 0.74 | PDE7A (0.55) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL11856128 | 0.74 | KMT2A (0.78) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL2639971 | 0.74 | MAPT (0.55) | PDE7ASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL27271638 | 0.74 | HSD17B10 (0.55) | PDE7ASMN1; SMN2PDE7BMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720983-B1 | Diphenyl disulfide compounds | NISSHIN FLOUR MILLING CO (JP) | 2001-03-14 | — | — | EP | disclosed |
| US-5698564-A | INHIBIT INTERLEUKINS AND TUMOR NECROSIS FACTOR | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |