Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209984 | 0.91 | PDE7A (0.56) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL11027382 | 0.91 | PDE7A (0.56) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL8734150 | 0.90 | PDE7A (0.51) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL11319431 | 0.89 | PDE7A (0.55) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL83607 | 0.87 | PDE7A (0.53) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL875772 | 0.86 | PDE7A (0.78) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL31272173 | 0.86 | PDE7A (0.78) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL1896221 | 0.84 | PDE7A (0.58) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL3384869 | 0.84 | PDE7A (0.58) | PDE7ASMN1; SMN2HSD17B10MAPTMEN1 | |
| SCHEMBL7758949 | 0.84 | PDE7A (0.54) | PDE7ASMN1; SMN2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 877 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163101-A1 | METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE | Research & Business Foundation Sungkyunkwan University (KR) | 2025-05-22 | — | — | US | claimed |
| EP-4488290-A1 | METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE | ABTIS Co., Ltd. (KR) | 2025-01-08 | — | — | EP | claimed |
| WO-2023167564-A1 | METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE | 앱티스 주식회사 | 2023-09-07 | — | — | WO | claimed |
| CN-115521234-B | Synthesis method of o-aminothiophenol | 苏州开元民生科技股份有限公司 | 2023-03-24 | — | — | CN | claimed |
| US-9242011-B2 | Insulin albumin conjugates | NOVO NORDISK A/S (DK) | 2016-01-26 | — | — | US | claimed |
| EP-2262539-B1 | INSULIN ALBUMIN CONJUGATES | NOVO NORDISK AS (DK) | 2015-07-15 | — | — | EP | claimed |
| US-20140235565-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-21 | — | — | US | claimed |
| US-8236945-B2 | Process for preparing disulfides and thiosulphinates and compounds prepared | Universite Joseph Fourier (Grenoble1) (FR) | 2012-08-07 | — | — | US | claimed |
| US-20110039769-A1 | INSULIN ALBUMIN CONJUGATES | NOVO NORDISK A/S (DK) | 2011-02-17 | — | — | US | claimed |
| US-7732534-B2 | Polymers functionalized with nitro compounds | BRIDGESTONE CORPORATION (JP) | 2010-06-08 | — | — | US | claimed |
| US-6960629-B2 | Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions | ACUSHNET COMPANY (US) | 2005-11-01 | — | — | US | claimed |
| US-20040230006-A1 | Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2004-11-18 | — | — | US | claimed |
| US-20040230005-A1 | Use of a metallic mercaptothiazole or metallic mercaptobenzothiazole in golf ball compositions | ACUSHNET COMPANY | 2004-11-18 | — | — | US | claimed |
| EP-1015402-B1 | Method for producing compounds containing fluorine, in particular fluorobenzaldehydes and fluorobenzonitriles | CLARIANT GMBH (DE) | 2002-12-04 | — | — | EP | claimed |
| US-6166242-A | Method for producing compounds containing fluorine, in particular fluorobenzaldhydes and fluorobenzonitriles | AVENTIS RESEARCH & TECHNOLOGIES GMBH & CO KG (DE) | 2000-12-26 | — | — | US | claimed |
| EP-0756611-B1 | PREPARATION PROCESS FOR POLYMER-MODIFIED BITUMEN | SHELL INT RESEARCH (NL) | 1998-03-04 | — | — | EP | claimed |
| EP-0658544-B1 | Improved process for the preparation of 2,2'-dinitrodiphenyl disulfide | BAYER AG (DE) | 1997-10-22 | — | — | EP | claimed |
| EP-0693056-A1 | PROCESS FOR THE PREPARATION OF ARYL- AND HETEROARYLSULPHURPENTAFLUORIDES | ZENECA LIMITED (GB) | 1996-01-24 | — | — | EP | claimed |
| EP-0658544-A1 | Improved process for the preparation of 2,2'-dinitrophenyl disulfide | BAYER AG (DE) | 1995-06-21 | — | — | EP | claimed |
| WO-1994022817-A1 | PROCESS FOR THE PREPARATION OF ARYL- AND HETEROARYLSULPHURPENTAFLUORIDES | ZENECA LIMITED (GB) | 1994-10-13 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110039769-A1 | INSULIN ALBUMIN CONJUGATES | ALB, IAPP, IGFBP1 | PDE7A 4256/4885SMN1; SMN2 2279/4885HSD17B10 1264/4885 |
| US-20250163101-A1 | METHOD FOR INCREASING PRODUCTION YIELD OF ANTIBODY-DRUG CONJUGATE BY USING THIOL-REACTIVE ADDITIVE | TST, DHFR, FCGRT | PDE7A 918/4885SMN1; SMN2 4192/4885HSD17B10 923/4885 |
| US-20140235565-A1 | N-ALKYLTHIO BETA-LACTAMS, ALKYL-COENZYME A ASYMMETRIC DISULFIDES, AND ARYL-ALKYL DISULFIDES AS ANTI-BACTERIAL AGENTS | COASY, SQOR, TST | PDE7A 1520/4885SMN1; SMN2 2837/4885HSD17B10 160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.