Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15244283 | 0.89 | DRD4 (0.42) | MAPTMEN1KMT2ALMNADRD4 | |
| SCHEMBL11665864 | 0.88 | MEN1 (0.38) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL15244041 | 0.87 | S1PR4 (0.48) | DRD4HSPB1CA2CYP19A1 | |
| SCHEMBL12518685 | 0.85 | DRD4 (0.45) | MAPTDRD4CYP1A2CA2SMN1; SMN2 | |
| SCHEMBL3701823 | 0.83 | MAPT (0.51) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL30121999 | 0.83 | MAPT (0.51) | MAPTMEN1KMT2ALMNAKDM4E | |
| SCHEMBL7561668 | 0.83 | DRD4 (0.40) | MEN1KMT2ALMNAPKMDRD4 | |
| SCHEMBL12661586 | 0.80 | CHRNB4 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1073697 | 0.80 | CHRNB4 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL466047 | 0.80 | CHRNB4 (0.53) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851864-B1 | NOVEL COUPLING AGENTS, PROCESSES FOR THEIR PREPARATION AND HAIR DYES | SCHWARZKOPF GMBH HANS (DE) | 2001-05-23 | — | — | EP | disclosed |
| US-5961668-A | 4-(2,4-diaminophenoxymethyl)-1,3-dioxolane secondary intermediates, processes for their production, and hair colorants | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1999-10-05 | — | — | US | disclosed |