Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8861461 | 0.83 | GAA (0.42) | GAAVDRCA2CA1CA12 | |
| SCHEMBL8796340 | 0.81 | GAA (0.41) | GAAVDRCA2CA1CA12 | |
| SCHEMBL2849488 | 0.80 | GAA (0.46) | GAAVDRCA2CA1CA12 | |
| SCHEMBL3521316 | 0.79 | GAA (0.45) | GAAVDRCA2CA1CA12 | |
| SCHEMBL9767627 | 0.77 | GAA (0.46) | GAAVDRCA2CA1CA12 | |
| SCHEMBL7186972 | 0.75 | GAA (0.59) | GAAVDRCA2CA1CA12 | |
| SCHEMBL12846997 | 0.74 | GAA (0.52) | GAAVDRCA2CA1CA12 | |
| SCHEMBL10402377 | 0.74 | AGER (0.44) | GAAVDRCA2CA1CA12 | |
| SCHEMBL890642 | 0.72 | GAA (0.50) | GAAVDRCA2CA1CA12 | |
| SCHEMBL476786 | 0.72 | GAA (0.54) | GAAVDRCA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727477-B1 | Ash-free detergents, their preparation, and use in lubricating oil compositions | LUBRIZOL ADIBIS HOLDINGS LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-5780403-A | Ash-free detergents their preparation and use in lubricating oil compositions | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1998-07-14 | — | — | US | disclosed |
| EP-0727477-A2 | Ash-free detergents, their preparation, and use in lubricating oil compositions | BP CHEMICALS (ADDITIVES) LIMITED (GB) | 1996-08-21 | — | — | EP | disclosed |