Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 15/20 | 0.70 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.70 |
| ▸ | NQO2 | P16083 | 3/20 | 0.70 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869477 | 0.98 | MTNR1A (0.74) | MTNR1AMTNR1BNQO2TP53MAPT | |
| SCHEMBL8867347 | 0.97 | MTNR1A (0.72) | MTNR1AMTNR1BNQO2TP53 | |
| SCHEMBL8867014 | 0.95 | MTNR1A (0.71) | MTNR1AMTNR1BNQO2TP53MAPT | |
| SCHEMBL8867809 | 0.92 | MTNR1A (0.70) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8867645 | 0.90 | MTNR1A (0.64) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8868522 | 0.89 | MTNR1A (0.62) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8868056 | 0.88 | MTNR1A (0.63) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8868079 | 0.88 | MTNR1A (0.73) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8868370 | 0.86 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL8868023 | 0.85 | MTNR1A (0.56) | MTNR1AMTNR1BNQO2TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721947-B1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-03-14 | — | — | EP | disclosed |
| US-5703121-A | SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1997-12-30 | — | — | US | disclosed |
| EP-0721947-A1 | Alkyl(hetero)cyclic compounds, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-07-17 | — | — | EP | disclosed |