Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14805320 | 0.85 | CYP1A2 (0.67) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL140815 | 0.83 | CYP1A2 (0.65) | CYP1A2GPBAR1MGAMCYSLTR1CYSLTR2 | |
| SCHEMBL5503169 | 0.81 | CYP1A2 (0.63) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL4623799 | 0.81 | CYP1A2 (0.68) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL29877127 | 0.81 | CYP1A2 (0.63) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL28635312 | 0.80 | CYP1A2 (0.61) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL29558951 | 0.80 | CYP1A2 (0.61) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL17372711 | 0.79 | CYP1A2 (0.64) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 | |
| SCHEMBL18530698 | 0.79 | HDAC1 (0.61) | CYP1A2GPBAR1MGAMMAPTGAA | |
| SCHEMBL30436901 | 0.79 | CYP1A2 (0.59) | CYP1A2GPBAR1MGAMMAPTCYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207833-B1 | REACTING 2-CHLOROQUINOLINE WITH MERCAPTOACETIC ACID | LOBA FEINCHEMIE AG (AU) | 2001-03-27 | — | — | US | disclosed |
| JP-2001031653-A | PRODUCTION OF 2-QUINOLINYLTHIOACETIC ACID OR ITS HYDROCHLORIDE | LOBA FEINCHEMIE AG | 2001-02-06 | — | — | JP | disclosed |
| EP-1063233-A1 | Process for the preparation of 2-quinolinylthio-acetic acid and its hydrochloride | LOBA FEINCHEMIE AKTIENGESELLSCHAFT (AT) | 2000-12-27 | — | — | EP | disclosed |
| EP-0631176-B1 | Photothermographic materials | EASTMAN KODAK CO (US) | 2000-12-13 | — | — | EP | disclosed |
| US-5594143-A | IMAGE STABILIZERS, ANTIFOGGING AGENTS | IMATION CORP. (US) | 1997-01-14 | — | — | US | disclosed |
| US-5460938-A | Containing a halogenated, sulfone-containing quinoline compound as antifogging agent | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| EP-0631176-A1 | Photothermographic materials | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-12-28 | — | — | EP | disclosed |