Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.64 |
| ▸ | CTSK | P43235 | 11/20 | 0.64 |
| ▸ | CTSB | P07858 | 6/20 | 0.64 |
| ▸ | CTSL | P07711 | 4/20 | 0.64 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7765852 | 0.87 | CTSS (0.66) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL1329147 | 0.85 | CTSS (0.56) | CTSSCTSKCTSBCTSL | |
| SCHEMBL1329145 | 0.85 | CTSS (0.56) | CTSSCTSKCTSBCTSL | |
| SCHEMBL14485901 | 0.85 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL8830310 | 0.84 | CTSS (0.60) | CTSSCTSKCTSBCTSLTACR1 | |
| SCHEMBL8443308 | 0.84 | CTSS (0.60) | CTSSCTSKCTSBCTSLTACR1 | |
| SCHEMBL14598315 | 0.84 | CTSS (0.64) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL19837597 | 0.82 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL18154315 | 0.82 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL11123304 | 0.82 | CTSS (0.69) | CTSSCTSKCTSBCTSLAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1101492-A1 | NOVEL REMEDIES FOR ALLERGIC DISEASES | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2001-05-23 | — | — | EP | disclosed |
| EP-1038864-A1 | NOVEL METALLOPROTEINASE INHIBITORS | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 2000-09-27 | — | — | EP | disclosed |