Butylamine

Butylamine

SCHEMBL7759176

CC(C)(C)CC(C)(C)c1ccc(O)cc1.CC(C)(C)CC(C)(C)c1ccc(O)cc1.CCCCN

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 2/20 0.70
ESR1 P03372 10/20 0.47
ESR2 Q92731 7/20 0.47
CYP3A4 P08684 4/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
SLC6A3 Q01959 3/20 0.39
LMNA P02545 2/20 0.39
HSD17B10 Q99714 2/20 0.39
TYR P14679 1/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
HIF1A Q16665 2/20 0.37
CYP2D6 P10635 1/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butylamine SCHEMBL27461778 1.00 SHBG (0.70) SHBGESR1ESR2CYP3A4SMN1; SMN2
Butylamine SCHEMBL28296259 0.98 SHBG (0.68) SHBGESR1ESR2CYP3A4SMN1; SMN2
Butylamine SCHEMBL27780646 0.98 SHBG (0.68) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL31282065 0.84 SHBG (1.00) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL10141 0.84 SHBG (1.00) SHBGESR1ESR2CYP3A4SMN1; SMN2
Butylamine SCHEMBL6904543 0.82 SHBG (0.44) SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6
Butylamine SCHEMBL7760156 0.82 ESR1 (0.50) SHBGESR1ESR2
Butylamine SCHEMBL6905397 0.82 ESR1 (0.50) SHBGESR1ESR2
SCHEMBL22773183 0.82 SHBG (0.95) SHBGESR1ESR2CYP3A4SMN1; SMN2
SCHEMBL10785821 0.82 SHBG (0.95) SHBGESR1ESR2CYP3A4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1084175-A1 CRYSTALLINE MODIFICATION OF MIXTURES OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION Great Lakes Chemical (Europe) GmbH (CH) 2001-03-21 EP disclosed
WO-1999055768-A1 CRYSTALLINE MODIFICATION OF MIXTURES OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) 1999-11-04 WO disclosed