Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.77 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.77 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.77 |
| ▸ | NPC1 | O15118 | 9/20 | 0.69 |
| ▸ | RAB9A | P51151 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.69 |
| ▸ | MEN1 | O00255 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL77958 | 0.88 | SMN1; SMN2 (0.77) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL20791858 | 0.88 | SMN1; SMN2 (0.77) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL704723 | 0.87 | SMN1; SMN2 (1.00) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL20791859 | 0.86 | NPC1 (0.76) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL1968036 | 0.85 | NPC1 (0.62) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL17175811 | 0.85 | SMN1; SMN2 (0.72) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL31729501 | 0.84 | SMN1; SMN2 (0.63) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL16607196 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL77204 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL22728466 | 0.83 | NPC1 (0.66) | SMN1; SMN2TAS1R3TAS1R1TAS1R2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | SMN1; SMN2 4339/4885TAS1R3 646/4885TAS1R1 682/4885 |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | SMN1; SMN2 4458/4885TAS1R3 725/4885TAS1R1 748/4885 |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | SMN1; SMN2 4328/4885TAS1R3 659/4885TAS1R1 669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.