SCHEMBL7759244

SCHEMBL7759244

CCN(CC)c1ccc(NC2(NC(C)=O)C(=O)N(c3ccccc3)N=C2Nc2ccc(OC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.39
NOX1 Q9Y5S8 2/20 0.38
ALDH1A1 P00352 5/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MAPK1 P28482 2/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
HPGD P15428 2/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
KDM1A O60341 1/20 0.36
KDM4E B2RXH2 2/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761051 0.93 MEN1 (0.44) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL7760958 0.91 MEN1 (0.40) MAPTNOX1ALDH1A1MAPK1GAA
SCHEMBL9400452 0.90 NPC1 (0.42) MAPTALDH1A1SMN1; SMN2RAB9AMEN1
Diethylamine SCHEMBL7759248 0.89 MAPT (0.40) MAPTALDH1A1MAPK1RAB9AMEN1
SCHEMBL9400440 0.88 NPC1 (0.44) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL7756064 0.88 NOX1 (0.38) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL9400364 0.86 MCHR1 (0.43) MAPTNOX1ALDH1A1SMN1; SMN2RAB9A
SCHEMBL9400382 0.86 MEN1 (0.45) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL7756057 0.86 ALDH1A1 (0.38) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1
SCHEMBL7760980 0.85 LCK (0.41) MAPTNOX1ALDH1A1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed