SCHEMBL7759250

SCHEMBL7759250

CC(=O)NC1(Nc2ccc(N(C)C)cc2)C(=O)N(c2ccccc2)N=C1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 10/20 0.39
KMT2A Q03164 10/20 0.39
MAPT P10636 9/20 0.39
ALDH1A1 P00352 8/20 0.39
TDP1 Q9NUW8 5/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
KDM4E B2RXH2 3/20 0.39
THRB P10828 3/20 0.39
LMNA P02545 3/20 0.39
PKM P14618 2/20 0.39
OPRK1 P41145 1/20 0.39
HTT P42858 1/20 0.39
GAA P10253 3/20 0.39
RAB9A P51151 2/20 0.39
GFER P55789 1/20 0.36
NR3C1 P04150 1/20 0.36
MAPK8 P45983 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761084 0.89 NOX1 (0.45) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL9400406 0.89 KCNK3 (0.42) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL7759212 0.88 MEN1 (0.37) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
Dimethylamine SCHEMBL7759251 0.87 SMN1; SMN2 (0.44) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL7760663 0.85 MAPT (0.37) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL9400419 0.84 KCNK3 (0.43) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
Diethylamine SCHEMBL7761090 0.83 SMN1; SMN2 (0.41) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL7762404 0.82 MAPT (0.39) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL7760648 0.80 CNR2 (0.43) SMN1; SMN2MEN1KMT2AMAPTALDH1A1
SCHEMBL7756010 0.78 MAPT (0.44) SMN1; SMN2MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed