SCHEMBL7760648

SCHEMBL7760648

CCN(CC)c1ccc(NC2(NC(=O)c3ccccc3)C(=O)N(c3ccccc3)N=C2C)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 1/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
NOX1 Q9Y5S8 1/20 0.43
MAPT P10636 5/20 0.42
GFER P55789 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ESRRG P62508 1/20 0.41
GHSR Q92847 1/20 0.39
HCRTR1 O43613 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
LMNA P02545 4/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TP53 P04637 1/20 0.38
NFKB1 P19838 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761084 0.91 NOX1 (0.45) CNR2MEN1KMT2ANPC1RAB9A
SCHEMBL7760668 0.89 CNR2 (0.41) CNR2MEN1KMT2ANPC1RAB9A
SCHEMBL9400401 0.89 MAPT (0.44) CNR2MEN1KMT2ANPC1RAB9A
SCHEMBL9400406 0.89 KCNK3 (0.42) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL7759221 0.88 CNR2 (0.40) CNR2MEN1KMT2ANPC1RAB9A
SCHEMBL7759279 0.87 GHSR (0.40) CNR2MEN1KMT2ANPC1RAB9A
Diethylamine SCHEMBL7760658 0.85 HSD17B10 (0.40) CNR2MEN1KMT2ANPC1RAB9A
Dimethylamine SCHEMBL9400409 0.85 SMN1; SMN2 (0.42) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL7761024 0.84 MAPT (0.43) CNR2MEN1KMT2ANPC1RAB9A
SCHEMBL7760674 0.84 KMT2A (0.41) CNR2MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0665462-B1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO LTD (JP) 2001-04-18 EP disclosed
US-5565306-A SUBSTRATE HAVING RECORDING LAYER CONTAINING PYRAZOLONE DERIVATIVE, HYDROQUINONE DERIVATIVE, ACIDIC SUBSTANCE MUTUALLY DISSOLVED THEREIN NEW OJI PAPER CO., LTD. (JP) 1996-10-15 US disclosed
EP-0665462-A1 Thermofixable photosensitive recording material and process for preparing thereof NEW OJI PAPER CO., LTD. (JP) 1995-08-02 EP disclosed
US-5372917-A Excellent color forming property, storage stability and recorded image preservability; pyrazolone derivatives KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1994-12-13 US disclosed