Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | SLC28A3 | Q9HAS3 | 2/20 | 0.41 |
| ▸ | FGF1 | P05230 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27518974 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL5246158 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL2244357 | 1.00 | L3MBTL1 (0.46) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL9562278 | 0.98 | L3MBTL1 (0.49) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL8362539 | 0.98 | L3MBTL1 (0.49) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL8362536 | 0.98 | L3MBTL1 (0.49) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL6517774 | 0.86 | L3MBTL1 (0.47) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL7259429 | 0.86 | L3MBTL1 (0.47) | L3MBTL1MAPTALDH1A1GAATYR | |
| SCHEMBL4325452 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MAPTGAATYRCA12 | |
| SCHEMBL2097041 | 0.83 | L3MBTL1 (0.47) | L3MBTL1MAPTGAATYRCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727433-B1 | Process for the preparation of 1-(2'-deoxy-2',2'-difluoro-d-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | LILLY CO ELI (US) | 2001-03-14 | — | — | EP | disclosed |
| US-5608043-A | Process for the preparation of 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose compounds | ELI LILLY AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5559222-A | Preparation of 1-(2'-deoxy-2',2'-difluoro-D-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-β-D-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0727433-A1 | Process for the preparation of 1-(2'-deoxy-2',2'-difluoro-d-ribo-pentofuranosyl)-cytosine from 2-deoxy-2,2-difluoro-beta-d-ribo-pentopyranose | ELI LILLY AND COMPANY (US) | 1996-08-21 | — | — | EP | disclosed |