Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.45 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | NRP1 | O14786 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759489 | 1.00 | MAPK8 (0.45) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL32690494 | 0.88 | NRP1 (0.46) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL30811140 | 0.88 | NMUR2 (0.49) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL30962076 | 0.87 | GRB2 (0.50) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL31380449 | 0.87 | NMUR2 (0.48) | MAPK8MAPK9MAPK10NMUR2NMUR1 | |
| SCHEMBL24485493 | 0.87 | F2 (0.49) | NMUR2NMUR1GRB2NRP1F2 | |
| SCHEMBL6806022 | 0.87 | SLC6A2 (0.43) | NMUR2NMUR1GRB2OPRM1OPRD1 | |
| SCHEMBL6806030 | 0.87 | SLC6A2 (0.43) | NMUR2NMUR1GRB2OPRM1OPRD1 | |
| SCHEMBL30307576 | 0.86 | NRP1 (0.47) | NMUR2NMUR1GRB2NRP1EPHA2 | |
| SCHEMBL30424443 | 0.86 | F2 (0.50) | NMUR2NMUR1GRB2NRP1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1089765-A2 | $i(IN VIVO) DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | Phenome Sciences Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-2000000636-A2 | IN VIVO DETERMINATION OF METABOLIC FUNCTION FOR USE IN THERAPY MANAGEMENT | PHENOME SCIENCES INC. (US) | 2000-01-06 | — | — | WO | disclosed |