Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759558 | 1.00 | KDM1A (0.38) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7759550 | 0.97 | L3MBTL1 (0.36) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7759555 | 0.97 | L3MBTL1 (0.36) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8415929 | 0.92 | KDM1A (0.40) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7759939 | 0.92 | KDM1A (0.40) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL7759942 | 0.92 | KDM1A (0.40) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8415932 | 0.92 | KDM1A (0.40) | KDM1ARCOR1CYP2C9ALDH1A1LMNA | |
| SCHEMBL8372072 | 0.90 | KDM1A (0.40) | KDM1ARCOR1SPHK1HDAC3HDAC1 | |
| SCHEMBL8372074 | 0.90 | KDM1A (0.40) | KDM1ARCOR1SPHK1HDAC3HDAC1 | |
| SCHEMBL8418659 | 0.89 | ESR2 (0.33) | KDM1ARCOR1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |