SCHEMBL7759899

SCHEMBL7759899

CCC(CC)([Si](C)(C)C)P(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 15/20 0.37
GGPS1 O95749 7/20 0.33
LMNA P02545 1/20 0.33
SMPD1 P17405 2/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1264209 0.77 FDPS (0.32) FDPS
SCHEMBL8463440 0.74 FDPS (0.37) FDPSGGPS1LMNASMPD1LPAR1
SCHEMBL1264479 0.73 FDPS (0.33) FDPSGGPS1LPAR1LPAR3
SCHEMBL11730591 0.72 FDPS (0.32) FDPS
SCHEMBL246809 0.65 FDPS (0.43) FDPSGGPS1LMNASMPD1LPAR1
SCHEMBL6296955 0.65 FDPS (0.43) FDPSGGPS1LMNASMPD1LPAR1
SCHEMBL8718782 0.65 GGPS1 (0.50) FDPSGGPS1LMNASMPD1LPAR1
SCHEMBL1768259 0.65 FDPS (0.43) FDPSGGPS1LMNASMPD1LPAR1
SCHEMBL16615961 0.65 FDPS (0.50) FDPSGGPS1SMPD1LPAR1LPAR3
SCHEMBL4828598 0.63 FDPS (0.41) FDPSGGPS1LMNASMPD1LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0667562-B1 Charge injection barrier for positive charging organic photoconductor HEWLETT PACKARD CO (US) 2001-03-21 EP claimed