Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759592 | 0.87 | CYP2C9 (0.36) | CYP2C9SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7507561 | 0.77 | CYP2C9 (0.50) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8452476 | 0.77 | CYP2C9 (0.50) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7756551 | 0.77 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7594396 | 0.77 | CYP2C9 (0.50) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8452150 | 0.77 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL7511645 | 0.77 | CYP2C9 (0.40) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL10601806 | 0.75 | CYP2C9 (0.51) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL8464978 | 0.75 | CYP2C9 (0.51) | CYP2C9ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL9827758 | 0.74 | CYP2C9 (0.41) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |