Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759932 | 0.87 | CYP2C9 (0.32) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL8083694 | 0.86 | MAPT (0.35) | MAPTMEN1KMT2AMAPK1NPC1 | |
| SCHEMBL13345644 | 0.75 | CYP2C9 (0.58) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL4802377 | 0.73 | CYP2C9 (0.59) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL4802367 | 0.73 | CYP2C9 (0.59) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL10725943 | 0.71 | CYP2C9 (0.61) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL10727892 | 0.71 | CYP2C9 (0.61) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL21581465 | 0.71 | ESR2 (0.49) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL8215784 | 0.71 | CYP2C9 (0.61) | CYP2C9ESR2MAPTMEN1KMT2A | |
| SCHEMBL8983150 | 0.70 | CYP2C9 (0.49) | CYP2C9ESR2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711777-B1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHINETSU CHEMICAL CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| EP-0711777-A1 | Cyclohexanone compounds, a process for preparing the cyclohexanone compounds, and a process for preparing silacyclohexane-based compounds from the cyclohexanone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |