Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7756651 | 0.89 | MEN1 (0.32) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7759903 | 0.85 | TNF (0.34) | MEN1KMT2ATDP1TNFADORA3 | |
| SCHEMBL7758304 | 0.84 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7758302 | 0.84 | SMN1; SMN2 (0.33) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7756702 | 0.84 | SMN1; SMN2 (0.35) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7757670 | 0.84 | ALDH1A1 (0.36) | MEN1KMT2ATDP1TNFSMN1; SMN2 | |
| SCHEMBL7757675 | 0.84 | ALDH1A1 (0.36) | MEN1KMT2ATDP1TNFSMN1; SMN2 | |
| SCHEMBL7756712 | 0.84 | SMN1; SMN2 (0.35) | MEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL7757656 | 0.82 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL7758245 | 0.81 | MEN1 (0.38) | MEN1KMT2ATDP1TNFADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736015-B1 | ANTIVIRAL 2,4-PYRIMIDINDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RES INST CHEM TECH (KR) | 2001-03-07 | — | — | EP | disclosed |
| US-5747500-A | VIRICIDES FOR AIDS | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1998-05-05 | — | — | US | disclosed |
| EP-0736015-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995018109-A1 | NOVEL ANTIVIRAL 2,4-PYRIMIDINEDIONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-07-06 | — | — | WO | disclosed |