Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1538783 | 0.89 | MAOB (0.50) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL10894279 | 0.88 | TSHR (0.44) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL1847239 | 0.87 | TSHR (0.61) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL62723 | 0.87 | TSHR (0.67) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL11599553 | 0.85 | TSHR (0.54) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL11599794 | 0.85 | TSHR (0.48) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL11598972 | 0.85 | TSHR (0.48) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL11227961 | 0.85 | TSHR (0.54) | TSHRMAPK1CES2MGLLALDH1A1 | |
| SCHEMBL17329109 | 0.84 | TSHR (0.58) | TSHRMAPK1CES2MGLLALDH1A1 | |
| Fluoride SCHEMBL30661872 | 0.84 | TSHR (0.64) | TSHRMAPK1CES2MGLLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1142131-C | Process for preparing meta-(trifluoromethyl)benzoic acid | 上海试四赫维化工有限公司 | 2004-03-17 | — | — | CN | claimed |
| CN-1356306-A | Process for preparing meta-(trifluoromethyl)benzoic acid | SHISI HEWEI CHEMICAL CO LTD SH (CN) | 2002-07-03 | — | — | CN | claimed |
| US-6313337-B1 | Method of making benzoyl halides and nitriles | OCCIDENTAL CHEMICAL CORPORATION | 2001-11-06 | — | — | US | claimed |
| US-4296244-A | (3-Trifluoromethylphenyl)-alpha-hydroxyacetic acid and process for preparation | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-10-20 | — | — | US | claimed |
| US-4268687-A | Method of making methyl and ethyl esters of (3-trifluoromethylphenyl)-acetic acid | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1981-05-19 | — | — | US | claimed |
| US-4238413-A | (3-Trifluoromethyl)-benzoyl cyanide and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-12-09 | — | — | US | claimed |
| CN-112851501-A | Chemical tracer for fracturing and preparation method and application thereof | 中国石油大学(华东) | 2021-05-28 | — | — | CN | disclosed |
| CN-100500637-C | Preparation process of 3-trifluoro methyl benzoate | SHANGHAI KANGPENG CHEMISTRY CO (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-100500631-C | Process of preparing 3-trifluoromethyl benzoic acid | SHANGHAI KANGPENG CHEMISTRY CO (CN) | 2009-06-17 | — | — | CN | disclosed |
| CN-101066917-A | Process of preparing 3-trifluoromethyl benzoic acid | SHANGHAI KANGPENG CHEMISTRY CO (CN) | 2007-11-07 | — | — | CN | disclosed |
| CN-101066926-A | Prepn process of 3-trifluoro methyl benzoate | SHANGHAI KANGPENG CHEMISTRY CO (CN) | 2007-11-07 | — | — | CN | disclosed |
| CN-1142131-C | Process for preparing meta-(trifluoromethyl)benzoic acid | 上海试四赫维化工有限公司 | 2004-03-17 | — | — | CN | disclosed |
| CN-1142131-C | Process for preparing meta-(trifluoromethyl)benzoic acid | 上海试四赫维化工有限公司 | 2004-03-17 | — | — | CN | disclosed |
| US-4238413-A | (3-Trifluoromethyl)-benzoyl cyanide and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4238413-A | (3-Trifluoromethyl)-benzoyl cyanide and process for its production | HOOKER CHEMICALS & PLASTICS CORP. (US) | 1980-12-09 | — | — | US | disclosed |
| US-4178383-A | Fungicidally active oxime-ethers of isonitrosocyanoacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-11 | — | — | US | disclosed |
| US-4098894-A | FUNGICIDES AND BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4093669-A | HALOGEN TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-06-06 | — | — | US | disclosed |
| US-4079089-A | CONTACTING A BIS/TRICHLOROMETHYL/-BENZENE WITH HYDROGEN FLUORIDE, HALOGEN TRANSFER CATALYST | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |
| US-4079090-A | Preparation of trichloromethyl-trifluoro methyl-benzenes | BAYER AKTIENGESELLSCHAFT (DT) | 1978-03-14 | — | — | US | disclosed |