Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | PLAU | P00749 | 3/20 | 0.54 |
| ▸ | ELANE | P08246 | 3/20 | 0.54 |
| ▸ | NOS1 | P29475 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5662585 | 0.98 | F2 (0.53) | F2PLAUELANENOS1CYP2D6 | |
| SCHEMBL2381806 | 0.78 | F2 (0.66) | F2PLAUELANEMAPK1KLKB1 | |
| SCHEMBL28135638 | 0.72 | — | — | |
| SCHEMBL4667331 | 0.72 | LMNA (0.53) | F2PLAUELANEMAPK1MAPT | |
| SCHEMBL13083315 | 0.71 | — | — | |
| SCHEMBL673557 | 0.69 | F2 (0.51) | F2PLAUELANEMAPK1KLKB1 | |
| SCHEMBL16423718 | 0.68 | F2 (0.43) | F2PLAUELANEMAPK1MAPT | |
| Hydrochloric Acid SCHEMBL9125773 | 0.67 | MAPT (0.58) | F2PLAUMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9123488 | 0.67 | MAPT (0.44) | F2PLAUMAPTMEN1KMT2A | |
| SCHEMBL16260370 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001062242-A1 | PRODRUGS OF SUBSTITUTED CYCLOPENTANE AND CYCLOPENTENE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2001-08-30 | — | — | WO | disclosed |