Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15703282 | 0.77 | CES2 (0.53) | CES2CES1HSD11B1MGLLHDAC8 | |
| SCHEMBL8764650 | 0.77 | CES2 (0.41) | CES2CES1HSD11B1MGLLHDAC8 | |
| SCHEMBL127438 | 0.75 | — | — | |
| SCHEMBL2867269 | 0.74 | CES2 (0.46) | CES2CES1HSD11B1HDAC8HDAC6 | |
| SCHEMBL1155651 | 0.74 | CES2 (0.46) | CES2CES1HSD11B1HDAC8HDAC6 | |
| SCHEMBL1043598 | 0.74 | CES2 (0.46) | CES2CES1HSD11B1HDAC8HDAC6 | |
| SCHEMBL2772945 | 0.74 | CES2 (0.46) | CES2CES1HSD11B1HDAC8HDAC6 | |
| SCHEMBL24790711 | 0.73 | CES2 (0.36) | CES2CES1MGLLHDAC8HDAC6 | |
| SCHEMBL22631255 | 0.73 | CES2 (0.43) | CES2CES1HSD11B1MGLLHDAC8 | |
| SCHEMBL125829 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084183-A1 | GRANULAR FORM OF A MIXTURE OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION | Great Lakes Chemical (Europe) GmbH (CH) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999052977-A1 | GRANULAR FORM OF A MIXTURE OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION | GREAT LAKES CHEMICAL (EUROPE) GMBH (CH) | 1999-10-21 | — | — | WO | disclosed |