Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14742403 | 0.76 | — | — | |
| SCHEMBL14369404 | 0.76 | ESR1 (0.41) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL20642063 | 0.74 | ALDH1A1 (0.35) | MAPK1CYP3A4SMN1; SMN2 | |
| SCHEMBL10574423 | 0.72 | TSHR (0.43) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL7517287 | 0.68 | ESR1 (0.49) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL11498228 | 0.67 | ESR1 (0.36) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL14369405 | 0.65 | CYP3A4 (0.36) | ESR1LMNAMEN1KMT2ACYP3A4 | |
| SCHEMBL10574429 | 0.64 | ESR1 (0.34) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL10556954 | 0.64 | ESR1 (0.34) | ESR1LMNAL3MBTL1MEN1KMT2A | |
| SCHEMBL21333321 | 0.63 | SMN1; SMN2 (0.45) | MEN1KMT2AMAPK1CYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200291018-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2020-09-17 | — | — | US | claimed |
| EP-3652174-A1 | TAM KINASE INHIBITORS | Syros Pharmaceuticals, Inc. (US) | 2020-05-20 | — | — | EP | claimed |
| WO-2019014513-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2019-01-17 | — | — | WO | claimed |
| EP-0517658-B1 | Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione | CIBA GEIGY AG (CH) | 1997-01-29 | — | — | EP | claimed |
| US-5457143-A | Light, heat and oxydiation resistance | CIBA-GEIGY CORPORATION (US) | 1995-10-10 | — | — | US | claimed |
| EP-0517658-A1 | Stabilisation of polymeric organic materials by using synergistic mixtures comprising sterically hindered cyclic amines and derivatives of 3-pyrazolidinone or 1,2,4-triazolidine-3,5-dione | CIBA-GEIGY AG (CH) | 1992-12-09 | — | — | EP | claimed |
| EP-0045721-A2 | Piperidyl derivatives of triazine copolymers, process for their preparation and compositions stabilised with such derivatives | CIBA-GEIGY S.p.A. (IT) | 1982-02-10 | — | — | EP | claimed |
| US-20200291018-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2020-09-17 | — | — | US | disclosed |
| EP-3652174-A1 | TAM KINASE INHIBITORS | Syros Pharmaceuticals, Inc. (US) | 2020-05-20 | — | — | EP | disclosed |
| WO-2019014513-A1 | TAM KINASE INHIBITORS | SYROS PHARMACEUTICALS, INC. (US) | 2019-01-17 | — | — | WO | disclosed |
| CN-100379724-C | Inhibition of pulp and paper yellowing using nitroxides and other coadditives | CIBA SC HOLDING AG (CH) | 2008-04-09 | — | — | CN | disclosed |
| EP-1084183-A1 | GRANULAR FORM OF A MIXTURE OF A NICKEL-QUENCHER AND A BENZOPHENONE AND PROCESS FOR ITS PREPARATION | Great Lakes Chemical (Europe) GmbH (CH) | 2001-03-21 | — | — | EP | disclosed |
| CN-1270580-A | Inhibition of pulp and paper yellowing using nitroxides and other coadditives | CIBA SC HOLDING AG (CH) | 2000-10-18 | — | — | CN | disclosed |
| US-4459395-A | LIGHT, HEAT, AND OXIDATION STABILIZERS FOR POLYOLEFINS | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1984-07-10 | — | — | US | disclosed |
| EP-0031304-B1 | PIPERIDINE DERIVATIVES AS STABILIZERS FOR SYNTHETIC POLYMERS | CIBA-GEIGY S.p.A. (IT) | 1984-06-13 | — | — | EP | disclosed |
| US-4442250-A | HEAT, LIGHT, AND OXIDATION RESISTANCE | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1984-04-10 | — | — | US | disclosed |
| US-4369321-A | Piperidine derivatives which are stabilizers for synthetic polymers | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1983-01-18 | — | — | US | disclosed |
| EP-0045721-A2 | Piperidyl derivatives of triazine copolymers, process for their preparation and compositions stabilised with such derivatives | CIBA-GEIGY S.p.A. (IT) | 1982-02-10 | — | — | EP | disclosed |
| EP-0006564-B1 | 2-(3.5-DISUBSTITUTED-2-HYDROXYPHENYL)-2H-BENZOTRIAZOLES AND STABILIZED COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1981-12-30 | — | — | EP | disclosed |
| EP-0031304-A1 | Piperidine derivatives as stabilizers for synthetic polymers | CIBA-GEIGY S.p.A. (IT) | 1981-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291018-A1 | TAM KINASE INHIBITORS | MAP3K1, PIK3CA, MAP3K5 | ESR1 555/4885LMNA 3146/4885L3MBTL1 2810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.