Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.61 |
| ▸ | HTR1A | P08908 | 7/20 | 0.54 |
| ▸ | HTR2C | P28335 | 5/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437749 | 0.96 | SIGMAR1 (0.63) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9685601 | 0.87 | SIGMAR1 (0.60) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9484568 | 0.85 | SIGMAR1 (0.62) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8109892 | 0.85 | SIGMAR1 (0.55) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7766393 | 0.84 | SIGMAR1 (0.56) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL7759840 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL8114163 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9684939 | 0.84 | SIGMAR1 (0.61) | SIGMAR1HTR1AHTR2C | |
| Hydrochloric Acid SCHEMBL8871344 | 0.84 | SIGMAR1 (0.54) | SIGMAR1HTR1AHTR2C | |
| SCHEMBL9685737 | 0.83 | SIGMAR1 (0.64) | SIGMAR1HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | disclosed |
| CN-1050601-C | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 2000-03-22 | — | — | CN | disclosed |
| US-5512569-A | SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS | ADIR ET COMPAGNIE (FR) | 1996-04-30 | — | — | US | disclosed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | disclosed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |
| US-5084469-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1992-01-28 | — | — | US | disclosed |